Pretty Hard Cases follows Guns and Gangs detective Samantha Wazowski and Narcotics detective Kelly Duff, who by day are true action heroes. But by night, they're both grappling with loneliness, dysfunctional families and screwed-up love lives. Their friendship could help to balance each other out, if only they didn’t drive one another utterly insane.

Season 2 finds Sam and Kelly in brand new territory, both at work and in their personal lives. As official partners for the first time, they have never been better at blending their different skills to get the job done. In the spirit of moving forward, they’re also trying to leave their baggage behind. Sam is now an empty-nester with a new love life, while Kelly is forging fresh bonds with her estranged sisters. When they find themselves up against a new age gang that doesn’t operate by the same old rules, Sam and Kelly are forced to put their lives on the line as they attempt the riskiest takedown of their careers.

Newly reunited as partners in Guns and Gangs, Detectives Samantha Wazowski and Kelly Duff must risk their lives to take down a dangerous gang, and a deadly new synthetic drug.