After his grandmother Sachiko passes away, Hayato Kasukabe returns from Tokyo and inherits her cafe—Familia Café Terrace. He aims to demolish the cafe and convert it into a parking lot, only to discover that his grandmother had taken in five girls prior to her death. The girls—Ouka Makuzawa, Akane Hououji, Riho Tsukishima, Shiragiku Ono, and Ami Tsuruga—evidently shared a deep bond with Sachiko, and they naturally refuse to give up the place they call home. They convince Hayato to change his mind, albeit reluctantly. Through this encounter, Hayato eventually remembers his past with his grandmother as well as his love for the cafe. Now resolved to carry on his grandmother's legacy, Hayato enlists the girls to act as the "goddesses" that will ensure the preservation of this precious abode.

It has been months since Hayato Kasukabe decided to save his late grandmother's cafe, Familia Café Terrace, from permanently closing its doors. He and the five "goddesses" who serve as the cafe's mascots—Ouka Makuzawa, Akane Hououji, Riho Tsukishima, Shiragiku Ono, and Ami Tsuruga—persevere through all the hardships of maintaining a business to stay afloat for as long as possible. Rougher times await them when a new competitor cafe, Family, appears with the sole intent of bringing Familia down. To come out on top of this business competition, Hayato must use his wits, fortify his trust in the girls, and figure out how to entice customers to continue supporting Familia. To further complicate matters, the girls slowly begin to develop feelings for Hayato, causing tensions within the group. As this can potentially pose an even greater threat to Familia's survival, the five goddesses need to find a way to compromise and unite at all costs.