As season one begins, Astronaut and astrophysicist John Crichton becomes stranded on the other side of the universe when his Farscape module goes through a wormhole. He is taken in by the misfit alien passengers of the sentient ship Moya, a spacecraft that happens to be on the run from the militaristic “Peacekeepers.” Unfortunately, while the ship is docked and making repairs, Crichton tangles with a captive Peacekeeper named Aeryn --a beautiful and volatile woman who alerts her captain about the Moya, putting everyone on board in danger.

Season two finds John Crichton and the living ship Moya's crew with their hands full and as suspicious of each other as ever. Crichton possesses hidden knowledge that his new nemesis, Scorpious, will stop at nothing to get.

The journey has never been easy for lost American astronaut John Crichton, the escaped alien prisoners who are his friends, or their living ship, Moya. And in the third season the ride becomes wilder than ever when powerful issues of love, loyalty, and sacrifice loom large.

In season four, astronaut John Crichton and Aeryn end up together while the seeds of an uneasy alliance between Crichton and Scorpius comes to the rescue. Echoes of war begin as the reptilian Scarrans seek the wormhole technology Crichton knows to rule the universe.