E1
Australian author Bradley Trevor Greive is on the guest list.
E2
Adam Scott is interviewed.
E3
Kristen Bell talks up Season 3 of "House of Lies."
E4
Idris Elba is on the guest list, along with panelists Nick Swardson, Sarah Colonna and Michael Rosenbaum.
E5
Amy Adams is interviewed. On the panel: Moshe Kasher; Fortune Feimster; Dov Davidoff.
E6
An interview with Zosia Mamet. Also: Heather McDonald, Julian McCullough and Gary Valentine are on the panel.
E7
Taylor Schilling is interviewed. On the panel: Giulia Rozzi; Josh Wolf; Loni Love.
E8
John Leguizamo promotes his movie "Ride Along." On the panel: Leah Remini; Mary McCormack; Whitney Cummings.
E9
Kendall and Kylie Jenner promote the Season 9 premiere of "Keeping Up With the Kardashians."
E10
Heather Graham is interviewed. On the panel: John Caparulo, Claire Titelman and Ross Mathews.
E11
Emmy Rossum talks about Season 3 of "Shameless." Ben Gleib is on the panel, along with April Richardson and Ryan Stout.
E12
David Spade ("The Spoils of Babylon") is on the guest list.
E13
Gabourey Sidibe talks about her role on "American Horror Story: Coven." On the panel: Kerri Kenney-Silver; Natasha Leggero; Bobby Lee.
E14
Timothy Olyphant chats about Season 5 of "Justified." On the panel: Michael Yo; Jamie Lee; Ross Mathews.
E15
Andy Samberg is interviewed. On the panel: Moshe Kasher; Loni Love; and Gary Valentine.
E16
Gabrielle Union is interviewed. On the panel: Ron G; Heather McDonald; Ian Karmel.
E17
Emma Roberts is interviewed. On the panel: Chris Franjola; Sarah Colonna; Dustin Ybarra.
E18
Vanessa Hudgens is interviewed. On the panel: John Caparulo; Fortune Feimster; Julian McCullough.
E19
Michelle Monaghan ("True Detective") is on the guest list. Panelists: Natasha Leggero; Sarah Tiana; Whitney Cummings.
E20
Mariska Hargitay is interviewed. On the panel: Jo Koy; Janine Brito; Ross Mathews.
E21
Emma Kenney ("Shameless") is on the guest list. Panelists: Brody Stevens; Jen Kirkman; Kurt Braunohler.
E22
Director McG ("3 Days to Kill"). Also: Jeff Wild, Cameron Esposito and Matt Braunger are on the panel.
E23
Sharon Osbourne.
E24
Chelsea celebrates Fashion Week. On the panel: Eliza Skinner; Lovi Love; Ryan Stout.
E25
Alison Brie is interviewed. On the panel: Kerri Kenney-Silver; Liza Treyger; Josh Wolf.
E26
Demi Lovato is interviewed.
E27
Guest host Ross Mathews
E28
Alex Pettyfer is on the guest list.
E29
Scott Speedman talks about his role in the comedy "Barefoot."
E30
Kurt Russell chats about starring in "The Art of the Steal." On the panel: Sarah Colonna, Moshe Kasher and Fortune Feimster.
E31
Julianne Moore appears in support of her film "Non-Stop." On the panel: Jen Kirkman, Beth Stelling and Jo Koy.
E32
Sarah Paulson is interviewed. On the panel: John Caparulo, Morgan Murphy and April Richardson.
E33
Figure skaters Tara Lipinski and Johnny Weir are interviewed. Also: Dov Davidoff, Whitney Cummings and Tone Bell are on the panel.
E34
Michelle Dockery of "Downton Abbey" is interviewed. On the panel: Kurt Braunohler, Fortune Feimster and Dustin Ybarra.
E35
Cameron Diaz chats about writing "The Body Book."
E36
Guest host Gabourey Sidibe
E37
Guest host Khloe Kardashian
E38
Guest host Mary McCormack
E39
Minnie Driver is interviewed.
E40
Chelsea chats with Emily Mortimer about the HBO comedy series "Doll & Em."
E41
Adam Levine is interviewed.
E42
A pastor thinks the movie "Frozen" has a gay agenda, Steven Tyler is allegedly dating his younger assistant, passengers on a Carnival Cruise want lifetime retribution, and from "Tyler Perry's Single Moms Club" Tyler Perry is here.
E43
L.A had an earth quake this morning, the Malaysian airplane is still missing, Guinness beer pulls out of Saint Patrick's Day Parade, and from "Catch a Contractor" Adam Carolla is here.
E44
The Pope refused to meet with Russell Crowe, Billy D Williams performed on "Dancing With The Stars", the couple from "Little Couple, Big World" are separating and from "Divergent" Theo James is here.
E45
George Clooney has a new girlfriend, John Mayor is sueing Charlie Sheen's friend, The Duke porn star is getting rich, and from "Enlisted" Geoff Stults is here.
E46
Johnny Weir and his husband split up, Selfies are causing a rise in plastic surgery, Is Malaysian Flight 370 somewhere off the coast of Australia, and snowboard champion Shaun White is here.
E47
Drew Brees is interviewed.
E48
Jayma Mays is interviewed.
E49
Rapper Rick Ross is interviewed.
E50
Bradley Trevor Greive stops by with cute baby animals.
E51
Demián Bichir.
E52
Mark Cuban is interviewed.
E53
Don Cheadle is interviewed.
E54
Mindy Kaling is interviewed.
E55
Jamie Foxx is interviewed. Also: John Caparulo, Beth Stelling and Brad Wollack appear on the panel.
E56
Sebastian Stan chats about his role in "Captain America: The Winter Soldier." On the panel: Kerri Kenney-Silver; Dustin Ybarra; and Heather McDonald.
E57
Nikolaj Coster-Waldau is interviewed.
E58
Comedian Amy Schumer is interviewed. On the panel: April Richardson; Sarah Colonna; and Ross Mathews.
E59
Marlon Wayans is interviewed.
E60
Singer-songwriter Ellie Goulding is interviewed. On the panel: Bobby Lee; Whitney Cummings; and Julian McCullough.
E61
Brooklyn Decker is interviewed. On the panel: Michael Yo; Loni Love; and Matt Braunger.
E62
Guest host Khloe Kardashian
E63
Guest host T.J. Miller
E64
Guest hosts Loni Love
E65
Guest host Mary McCormack
E66
Giuliana and Bill Rancic are interviewed.
E67
Hugh Dancy ("Hannibal") is on the guest list.
E68
Helen Hunt discusses her role in the film "Decoding Annie Parker."
E69
Neon Trees' frontman Tyler Glenn is interviewed.
E70
Rapper 2 Chainz is interviewed. On the panel: Julian McCullough; Brad Wollack; and Liz Carey.
E71
Jane Lynch is interviewed. On the panel: Chris Franjola; April Richardson; Gary Valentine.
E72
Arianna Huffington is interviewed. On the panel: Jen Kirkman; Kevin Christy; and Josh Wolf.
E73
Dave Franco is interviewed. On the panel: Nick Thune; Ian Karmel; Heather McDonald.
E74
Connie Britton is interviewed.
E75
Sandra Oh is interviewed.
E76
Jason Priestley chats about his memoir.
E77
"Nurse Jackie" star Edie Falco is on the guest list.
E78
Evan Peters is on the guest list. On the panel: Ron Funches, Sarah Tiana and Brad Wollack.
E79
Australian rapper Iggy Azalea is interviewed. On the panel: Michael Yo; Bobby Lee; and Jo Koy.
E80
Charlize Theron is interviewed.
E81
Drew Barrymore and Adam Sandler are interviewed.
E82
Joel McHale is interviewed.
E83
Terry Crews is interviewed.
E84
Sarah Silverman.
E85
Lea Michele is interviewed.
E86
Kelly Osbourne is on the guest list.
E87
Giovanni Ribisi is interviewed. On the panel: Jeff Wild, Natasha Leggero and Josh Wolf.
E88
Singer Austin Mahone is interviewed.
E89
Colin Hanks is interviewed.
E90
Lena Headey is interviewed.
E91
Chelsea chats with Channing Tatum.
E92
Jenny Slate chats about her movie "Obvious Child." On the panel: Liza Treyger; Jen Kirkman; Julian McCullough.
E93
Rob Riggle is interviewed. On the panel: Moshe Kasher; Fortune Feimster; and Bobby Lee.
E94
Jason Biggs ("Orange Is the New Black") is interviewed.
E95
The cast of the Lifetime reality series "Little Women: LA" are on the guest list. Panelists include Greg Fitzsimmons, Sarah Tiana and Julian McCullough.
E96
Laverne Cox ("Orange Is the New Black"). On the panel: Chris Franjola; Michael Yo; Josh Wolf.
E97
Meagan Good appears in support of her movie "Think Like a Man Too." Also: Ben Gleib, Fortune Feimster and Ryan Stout are on the panel.
E98
Kevin Hart is interviewed.
E99
Jenna Dewan-Tatum chats about Season 2 of her Lifetime drama "Witches of East End."
E100
Comedian Gabriel Iglesias is on the guest list.
E101
Chris Rock is interviewed. On the panel: Brody Stevens; April Richardson; and Jo Koy.
E102
Eric Bana is interviewed about his starring role in the thriller "Deliver Us From Evil."
E103
Melissa McCarthy is interviewed. On the panel: Jeff Wild; Loni Love; Brad Wollack.
E104
Susan Sarandon is interviewed. On the panel: Chris Franjola; Arden Myrin; Kurt Braunohler.
E105
Bel Falcone is interviewed.
E106
Model Chrissy Teigen is interviewed. On the panel: Josh Wolf; Loni Love; Gary Valentine.
E107
Dane Cook is on the guest list. On the panel: Ben Gleib; Bobby Lee; Ross Mathews.
E108
Cameron Diaz is interviewed. On the panel: Mary McCormack; Whitney Cummings; Julian McCullough.
E109
Dean Norris ("Under the Dome") is interviewed.
E110
Lela Loren is interviewed.
E111
Frank Grillo, star of "The Purge: Anarchy," is interviewed.
E112
Natasha Lyonne and Uzo Aduba, stars of "Orange Is the New Black," are interviewed.
E113
E114
John C. Reilly is interviewed.
E115
Kelsey Grammer is interviewed.
E116
Chris Pratt is interviewed.
E117
E118
Country music artist Jake Owen is on the guest list.
E119
Ethan Hawke is interviewed.
E120
NBA player Chandler Parsons.
E121
Megan Fox is interviewed.
E122
Liv Tyler ("The Leftovers") is interviewed.
E129
In her opening monologue, host Chelsea Handler talks about what she did today at the studio on this the last day of the show, including the last communal shower she had in the Chelsea Lately shower facility. Chelsea and Chuy bring on her current stable of round table regulars. What Chelsea believes is going to be three of her closest celebrity friends, Mary McCormack - her best friend - Jennifer Aniston, and Sandra Bullock, providing a gracious send-off ends up being what they hope will be more useful for Chelsea's life. Chelsea's ex-lover 50 Cent and G-Unit perform their new single, "Watch Me". Chuy, via a prepared video, talks about what this show and Chelsea have meant to him. Miley Cyrus, in tribute to it being the last show, performs the pop classic, "It's Over". And many of Chelsea's musical friends, and some non-musical friends, help her serenade E!, to who she is grateful for the past seven years.