History's Biggest Political Blunder

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Jimmy Kimmel, Jen D'Angelo and Howard Bragman discuss history's biggest political blunder.

History's Worst Medical Advice

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Chris Hardwick, comic Jordan Carlos and scientist Bob Pflugfelder discuss history's worst medical advice.

History's Biggest Frenemies

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Courtney Cox, comedian Dan Soder and author/comedian Michael Ian Black debate and discuss history's biggest frenemies.

History's Most Doomed Presidential Campaign

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Guests Elijah Wood, comedian Bryan Callen and Professor Dan Schnur discuss history's most doomed presidential campaign.

History's Worst Tyrant

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Julie Bowen, Dan Levy and Laila Lalami discuss the worst tyrants in history.

History's Craziest Cult

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Jack Black, Tymberlee Hill and Stephen Prothero talk about crazy cults.

History's Greatest Invention Since 1950

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Trace Adkins, Kate Flannery and Lori Greiner talk about great inventions of the past half century.

History's Most Influential Band

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Lars Ulrich, Tom Papa and Alan Light talk about great rock bands,

History's Most Influential Drug

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David Eisenbach, Maria Bello and Derek Waters talk medicine.

History's Biggest Fall from Grace

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Jay Leno, Mark Forward and Howard Bragman

History's Greatest Man-Made Structure

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Adam Goldberg, Noel Wells and Ty Pennington talk great modern mysteries

History's Most Plausible Conspiracy Theory

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Judd Apatow, Kurt Braunohler and Mike Massimino don tin foil hats.

History's Biggest Presidential Bad Boy

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Angela Kinsey, Heather McDonald and Joel Stein talk bad boy presidents.

History's Dumbest Mistake

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Dan Riskin, Ian Abramson and Tim Meadows talk about the dumbest mistakes in history.

History's Greatest Unsolved Mystery

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Michael Ian Black, Josh Wolf and Jason Biggs channel Robert Stack for a look at famous unsolved mysteries.

History's Greatest Gangster

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Derrick Pitts, Thomas Dale and Joel McHale talk about the greatest gangsters to ever have lived.

History's Greatest Unexplained Phenomenon

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Mike Massimino, Megan Amram and Larry King talk about the greatest known unexplained phenomena.

History's Most Defiant Moments of the Last 75 Years

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John Avlon, Yvette Nicole Brown and Lisa Kudrow talk about big mmoments where people still revolt.

History's Best Founding Father

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Joel Stein, Jo Koy and Fred Willard discuss the founding fathers.

History's Biggest Fraud

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Joel Stein, Russell Peters and Michael Sheen talk about history's frauds.

History's Biggest Badass

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Evy Poumpouras, Mark Forward and Regis Philbin talk about the badasses of history.