Snot Now, Snot Ever
E1
A new recruit changes the dynamics in the lab as Snot Faucet's cold threatens a sticky end for everyone!
Pimple Fever
E2
When Septico's long lost brother comes to visit, he's repulsed by the grossness of the Yuck Lab - until he accidentally gets turned into a poop loving housefly.
Arachnattack
E3
A horrible, hairy monster is unleashed as Septico's arch-nemesis arrives for an inspection of the Yuck Lab.
Dirty Rotten Birthday Girl
E4
Septico's attempt to throw Pristine a birthday party turns into a disgusting food eating competition.
Fungus Humungus
E5
Pristine's fear of fungus could destroy the lab.
Enter the Toothworm
E6
Septico tries his hand at wormcharming and Pristine hides a toothache when their dentist Aunt comes to visit.
Septico's Felonious Funk
E7
Septico's quest to take his body odor to new stinktacular heights forces Pristine to redesign her latest invention, the Smell-O-Vac, for her...
That's So Fly
E8
When Septico's long lost brother comes to visit, he's repulsed by the grossness of the Yuck Lab - until he accidentally gets turned into a poop loving housefly.
Gastrov Flatulinsky
E9
Septico challenges World Fart Champion Gastrov Flatulinsky to a farting competition.
Attack of the Yucky Plants
E10
When Septico's college crush, Botany "expert" Egregious Flytrap visits the lab, the gang tries to impress her with various disgusting plants, not realizing she wants to use those plants in a diabolical experiment.
Urine Luck
E11
After Pristine turns down the chance to give a prestigious speech, Septico finds out she passed because she has urine control issues, and he's determined to whip her bladder in shape for her to give the speech.
Parasite Pirates
E12
When a crew of pirate parasites takes over the Yuck Lab and infects the gang, Septico has to figure out a cure for the various parasites.
No Guts, No Glory
E13
The lab gang is left in charge of an annoying little girl with a tummy ache, as they scramble to prepare their submission for the World Yuckology Expo.
The Yuck Trifecta
E14
When Pristine comes down with an increasingly more disgusting series of yucky conditions - Septico must save her from her body's own disgustingness.
Pristine Hair-Wolf
E15
A horrible, hairy monster is unleashed as Septico's arch-nemesis arrives for an inspection of the Yuck Lab.
Kung Poo
E16
Septico's quest to do the perfect poop brings an ancient and dangerous curse on the lab.
Antpocalypse Now!
E17
When the lab is overrun by an ant colony, Septico and the team have to bargain with the ants - before the O'Cleans can send in the Cleaners!
Yuck Lab Z
E18
Septico and Pristine seem to swap personalities after they're stung by zombie parasite wasps.
Roach Motel
E19
Septico's fascination with cockroaches causes chaos when he invites a specialist cockroach trainer to the lab.
The Big Stink
E20
Leonidis' locks down the lab when his favorite stinky sandwich gets stolen, so Septico has to expose the gang to various stinky animals to find the culprit.
Oh Rats!
E21
When it's revealed that Durp-E is secretly keeping a pet rat in the Yuck Lab, everyone is shocked as to whom the cringing, shrieking aversion to them is.
Everything's All-Mite!
E22
Septico and the gang try to stop the O'Cleans from destroying the world's Mite population by creating an ad campaign to show that microscopic mites are actually cool.
Around the S Bend
E23
A monstrous Fatberg emerges from the sewers to wreak havoc on the lab!
Blisters and Shingles and Warts! Oh My!
E24
All the gang get painful and gross skin conditions when Pristine attempts to cover her spying by helping Septico get into the record books for the world's biggest blister.
All's Yuck That Ends Yuck Part 1
E25
Reeling from Pristine's betrayal, Septico advertises for her replacement and is visited by a seemingly perfect candidate.
All's Yuck That Ends Yuck Part 2
E26
The fate of the lab is at stake as the gang is held hostage by their new boss.